Detection of seizure onset in childhood absence epilepsy.

OBJECTIVE: This study aims to detect the seizure onset, in childhood absence epilepsy, as early as possible. Indeed, interfering with absence seizures with sensory simulation has been shown to be possible on the condition that the stimulation occurs soon enough after the seizure onset. METHODS: We present four variations (two supervised, two unsupervised) of an algorithm designed to detect the onset of absence seizures from 4 scalp electrodes, and compare their performance with that of a state-of-the-art algorithm. We exploit the characteristic shape of spike-wave discharges to detect the seizure onset. Their performance is assessed on clinical electroencephalograms from 63 patients with confirmed childhood absence epilepsy. RESULTS: The proposed approaches succeed in early detection of the seizure onset, contrary to the classical detection algorithm. Indeed, the results clearly show the superiority of the proposed methods for small delays of detection, under 750 ms from the onset. CONCLUSION: The performance of the proposed unsupervised methods is equivalent to that of the supervised ones. The use of only four electrodes makes the pipeline suitable to be embedded in a wearable device. SIGNIFICANCE: The proposed pipelines perform early detection of absence seizures, which constitutes a prerequisite for a closed-loop system.

Estimation of muscular fatigue under electromyostimulation using CWT.

The aim of this study is to investigate muscular fatigue and to propose a new fatigue index based on the continuous wavelet transform (CWT) which is compared to the standard fatigue indexes from literature. Fatigue indexes are all based on the electrical activity of muscles [electromyogram (EMG)] acquired during an electrically stimulated contraction thanks to two modules (electromyostimulation + electromyography recording) that can analyze EMG signals in real time during electromyostimulation. The extracted parameters are compared with each other and their sensitivity to noise is studied. The effect of truncation of M waves is then investigated, enlightening the robustness of the index obtained using CWT.

A mixed FES/EMG system for real time analysis of muscular fatigue.

In this article, we present a functional electrical stimulator allowing the extraction in real time of M-wave characteristics from resulting EMG recodings in order to quantify muscle fatigue. This system is composed of three parts. A Labview software managing the stimulation output and electromyogram (EMG) input signal, a hardware part amplifying the output and input signal and a link between the two previous parts which is made up from input/output module (NIdaq USB 6251). In order to characterize the fatigue level, the Continuous Wavelet Transform is applied yielding a local maxima detection. The fatigue is represented on a scale from 0 for a fine shaped muscle to 100 for a very tired muscle. Premilary results are given.